【副教授】刘英帅
发布时间:2012-10-22 16:03:17     作者:liuzhaotun    浏览次数: 次

 

刘英帅男,山东荷泽人,中共党员,博士,副教授,硕士生导师。

 

联系方式:

Emailysliu@swu.edu.cn

电话: 023-68254943

 

学习和工作经历:

·         2011.9 -至今,西南大学,材料与能源学部,副教授,硕导

·         2011.2 -2011.9,新加坡南洋理工大学,研究助理/博士后研究员(Research Fellow)

·         2007.1-2011.1,新加坡南洋理工大学,化学与生物医学工程学院,博士

·         2006.1 -2007.1,新加坡南洋理工大学,研究助理(Research associate)

·         2003.9-2005.7,华中师范大学,生命科学学院,理学硕士

·         1999.9-2003.7,菏泽学院/鲁东大学,生命科学学院,理学学士

 

主要研究方向:

·         纳米材料的合成、表面修饰和功能化

·         微纳电子器件及生物/化学传感器

·         基于纳米材料高灵敏微阵列和微流控蛋白芯片的基础研究及技术开发

·         蛋白质芯片在疾病机理探讨、疾病诊断、食品安全检测等领域的应用

 

主持科研项目:

·         基于长余辉发光纳米探针的前列腺癌细胞表面聚糖原位分析, 国家自然科学基金(面上基金),2015.1-2018.12,项目负责人

·         应用微阵列芯片研究蛋白质O-GlcNAc糖基化在肿瘤发生中的作用及其机制,国家自然科学基金(青年基金),2013.1-2015.12,项目负责人

·         聚合物刷与核壳纳米粒子介导的协同信号放大及高灵敏免疫诊断芯片研究,重庆市自然科学基金,2012.9-2014.9,项目负责人

·         基于可控纳米共聚物刷的抗体定向固定及高灵敏医学检测芯片的研究,中央高校基本科研业务费,2012.1-2013.12,项目负责人

 

代表论文:

1.  Y. S. Liu, W. H. Hu, Z. S. Lu, C. M. Li: ZnO Nanomulberry and Its Significant Non-enzymatic Signal-Enhancement for Protein Microarray. ACS Appl. Mater. Inter., 2014, 6, 7728-7734.

2.  Y. S. Liu*, Y. Y. Zhang, Y. N. Zhao, J. Yu: Phenylboronic acid polymer brush-enabled oriented and high density antibody immobilization for sensitive microarray immunoassay. Colloids Surf. B: Biointerfaces, 2014, 121, 21-26.

3.  Y. S. Liu*, Y. N. Zhao, Y. Y. Zhang: One-step green synthesized fluorescent carbon nanodots from bamboo leaves for copper () ion detection. Sens. Actuat. B-Chem, 2014, 196, 647–652.

4.  Y. S. Liu, X. L. Li, S. J. Bao, Z. S. Lu, Q. Li, C. M. Li: Plastic protein microarray to investigate the molecular pathways of magnetic nanoparticle-induced nanotoxicity. Nanotechnology 2013, 24(17), 175501.

5.  Y. S. Liu, C. X. Guo, W. H. Hu, Z. S. Lu, C. M. Li: Sensitive protein microarray synergistically amplified by both polymer brush-immobilized probe and reporter. J. Colloid Interf. Sci. 2011, 360(2), 593-599.

6. Y. S. Liu, W. Wang, W. H. Hu, Z. S. Lu, X. Q. Zhou, C. M. Li: Highly Sensitive Poly[glycidyl methacrylate-co-poly(ethylene glycol) methacrylate] Brush-Based Flow-Through Microarray Immunoassay Device. Biomed. Microdevices 2011, 13(4), 769-777.

7. W. H. Hu#, Y. S. Liu#, H. B. Yang, X. Q. Zhou, and C. M. Li: ZnO Nanorods-Enhanced Fluorescence for Sensitive Microarray Detection of Cancers in Serum without Additional Reporter-Amplification. Biosens. Bioelectron., 2011, 26(8), 3683-3687. (Equal first author)

8. Y. S. Liu, W. H. Hu, Z. S. Lu, C. M. Li: Photografted poly(methyl methacrylate)-based high performance protein microarray for hepatitis B virus biomarker detection in human serum. Med. Chem. Comm., 2010, 1(2), 132-135.

9. Y. S. Liu, C. M. Li, W. H. Hu and Z. S. Lu: High performance protein microarrays based on glycidyl methacrylate-modified polyethylene terephthalate plastic substrate. Talanta, 2009, 77(3), 1165-1171.

10. Y. S. Liu, C. M. Li, L. Yu and P. Chen: Optimization of printing buffer for protein microarrays based on aldehyde-modified glass slides. Front. Biosci., 2007, 12, 3768-3773.

11. Y. S. Liu, C. M. Li, Z. S. Lu, S. M. Ding, X. Yang, J. Mo: Studies on formation and repair of formaldehyde-damaged DNA by detection of DNA-protein crosslink and DNA breaks. Front. Biosci. 2006, 11, 991-997.

12. W. H. Hu, Y. S. Liu, Z. S. Lu, C. M. Li: Poly(oligo(ethylene glycol) methacrylate-co-glycidyl methacrylate) Brush Substrate for Sensitive Surface Plasmon Resonance Imaging Protein Arrays. Adv. Funct. Mater., 2010, 20(20), 3497-3503.

13. W. H. Hu, Y. S. Liu, Z. H. Zhu, H. B. Yang and C. M. Li: Randomly Oriented ZnO Nanorods As Advanced Substrate for High-Performance Protein Microarrays. ACS Appl. Mater. Interfaces, 2010, 2(6), 1569-1572.

14. Z. S. Lu, Y. S. Liu, W. H. Hu, C. M. Li: Rewritable multicolor fluorescent patterns for multistate memory devices with high data storage capacity. Chem. Comm., 2011, 47(34), 9609-9611.

15. W. Wang, C. Yang, Y. S. Liu and C. M. Li: On-demand droplet release for droplet-based microfluidic system. Lab Chip, 2010, 10(5), 559-562.

 

申请和授权专利

1. 刘英帅,鲁志松,杨旭  DNA-蛋白质交联定量检测试剂盒。专利号:ZL2004 2 0111383.1

2. 李长明,刘英帅,张嫄媛:高通量三维微流控芯片免疫测定装置及其制备方法。申请号:201410260221.2

3.李长明,胡卫华,刘英帅微阵列生物芯片的三维载体及其制备方法。申请号: 201310058455

4. 李长明,胡卫华,刘英帅纳米氧化锌修饰的免疫毛细管及其制备方法和应用。申请号:201210550889.1